I was born twice: first, as a baby girl, on a remarkably smogless Detroit day in January 1960; and then again, as a teenage boy, in an emergency room near Petoskey, Michigan, in August of 1974.

So goes the opening sentence of Middlesex, a novel by Jeffrey Eugenides.

From Jeff Turrentine, The Los Angeles Times: “Eugenides has had nearly a decade to relax, and the happy result is a novel that’s as warm, expansive and generous as its predecessor wasn’t. (…) Among many things, Middlesex is the author’s love letter to a city that could probably use a few more. (…) Middlesex isn’t just a respectable sophomore effort; it’s a towering achievement, and it can now be stated unequivocally that Eugenides’ initial triumph wasn’t a one-off or a fluke. He has emerged as the great American writer that many of us suspected him of being.”

A review by Debbie Lee Wesselmann on Amazon.com:

From the first sentence of Jeffrey Eugenides’ MIDDLESEX, I was hooked by this complicated tale of a young girl who grows into a man. The story of Cal Stephanides begins generations before his birth, in a small Greek village, when his grandparents succumb to incestuous desires. Immigration to the United States keeps Desdemona and Lefty’s secret intact – until their grandchild Cal reaches puberty. Told with both humor and earnestness, the story grows more engaging with every page.

The brilliance of this book emerges not from the superficial story of a hermaphrodite but from the context – historical, scientific, psychological, political, geographical – of Cal’s birth and subsequent rebirth. MIDDLESEX is about much more than gender confusion. Cal’s mixed gender can be taken as a metaphor for the experience of first- and second-generations born of immigrants.

While the context of this story provides the substance, the characters provide the vibrancy. Cal emerges as a reliable and likeable narrator. He is sensible, good-humored, and intelligent. The spectrum of his experiences provides a smooth transition between childhood and adult, enabling the reader to embrace the character as both male and female. Cal’s family is affectionately portrayed, even with their failings. (Cal’s brother, Chapter Eleven, annoyed me with his name, a running gag, but even he ended up a full-blooded character by the end.)

Eugenides has written an expansive, compelling book. Despite its length of over 500 pages, the novel is not a slow read – unless the reader wants it to be, to make it last. Accessible, intelligent, well-paced and plotted, it should appeal to a wide range of readers.

I can’t recommend this novel highly enough.

Mother nature can be an inventive force, even cruel (considering the eye-of-the-beholder). In Cal’s case, the narrator and main character in Middlesex, he was born a hermaphrodite.  After his confused early years, he learned to accept his condition, even cherish it, though it led to challenges most of us can’t begin to imagine.

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Cal tells us his family history which leads to why he emerged in the world with characteristics of both sexes.  He tells us about his emotional and confused early years, his challenges and trials, his failed romances, and then how he came about to accept his unique fate.  It’s a must read for anyone looking for something different.